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Maulbronn, June 2023

Dear friends, donors and supporters of the LUKAS Foundation and the ISOREL® project!

We would like to express our sincere thanks for the high level of willingness to donate, as well as the enormous commitment in providing interest-free loans for the Lukas-Heilstätten GmbH.

Thanks to these great gifts, we have succeeded in obtaining the GMP permit from the AGES/BASG in November 2022. This is the pharmaceutical operating licence for the production and distribution of sterile drug injections.

Furthermore, Isorel has been on the market again in South Korea since January 2023. We were able to deliver a first very large batch there in December.

Distribution in Austria will start in the second half of 2023. In the area of contract manufacturing, ampoules from a well-known Austrian company are being validated. At the same time, further contract manufacturing orders of vital medicinal products as well as the production and validation of clinical investigational medicinal products are being completed.

As you can see, a number of positive developments are currently taking place due to your and our enormous commitment. This brings us a very important step closer to our common goal of providing good things for mankind.

Lukas Heilstätten GmbH is now entering the start-up phase of production. This step is connected with enormous investments and costs. Therefore, we ask you to continue to support us with donations and interest-free loans, if possible.

Thank you very much for this.

Kind regards

Dr. Wessel von Loe